Skip to content

Skin Conditioning

MATRINE

CAS 519-02-8
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Matrine — a Sophora root alkaloid with anti-inflammatory and antimicrobial activity. Pharmacologically active rather than a benign botanical; limited cosmetic safety data argues for moderate caution.

Skin benefits

  • Sophora root-derived alkaloid with anti-inflammatory activity
  • Studied for itch and irritation relief
  • Antimicrobial activity in vitro

Known concerns

  • Plant alkaloid with pharmacological activity; not a benign botanical
  • Limited cosmetic CIR/SCCS dossier
  • Systemic toxicity at oral high doses raises caution for cosmetic levels
  • Use with awareness, particularly in leave-on products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related skin conditionings

45
ADENIUM OBESUM LEAF EXTRACT
Skin Conditioning
 45
ADONIS AMURENSIS EXTRACT
Skin Conditioning
 45
AGERATUM CONYZOIDES LEAF EXTRACT
Skin Conditioning
 45
ANNONA SQUAMOSA SEED EXTRACT
Skin Conditioning
 45
ANTHRISCUS SYLVESTRIS EXTRACT
Skin Conditioning
 45
ARNEBIA NOBILIS ROOT EXTRACT
Skin Conditioning
 45
ASIVATREP
Skin Conditioning
 45
CAPSICUM ANNUUM RESIN
Skin Conditioning

Check your shelf

Find MATRINE in your products.

Scan any cosmetic product with LuxSense to see if it contains MATRINE and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.