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Mefeclorazine (INN) and its salts

CAS 1243-33-0
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Mefeclorazine (INN) and its salts is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Mefeclorazine is an International Nonproprietary Name (INN) designated phenothiazine derivative with neuroleptic (tranquilizer) properties. The INN designation confirms its status as a recognized pharmaceutical substance. Phenothiazine derivatives have effects on the central nervous system and are classified as pharmacologically active substances. Under EU Cosmetics Regulation, such substances are prohibited from cosmetic use as they are not intended to act merely on the skin structure but rather have systemic drug-like effects.

Known concerns

  • Pharmaceutical neuroleptic substance
  • CNS-active pharmacologic effects
  • Prohibited in cosmetic formulations under EU regulations

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.