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Antioxidant

MELATONIN

CAS 73-31-4
78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

The body's sleep hormone, also a strong antioxidant when applied to skin. Generally safe topically but its systemic activity makes most regulators cautious.

Skin benefits

  • Endogenous antioxidant
  • Free-radical scavenger in skin
  • Photoprotection adjunct

Known concerns

  • Hormone-active in oral use — caution on dermal absorption
  • Dose-response unclear in cosmetics
  • Avoid in pregnancy products as precaution

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.