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MENTHANE CARBOXAMIDOETHYL ACETATE

CAS 39668-74-1 / 68489-14-5
38

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Menthane Carboxamidoethyl Acetate is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

This compound is a menthane carboxamide derivative structurally related to menthol (menthyl carboxamide - N-ethyl-2,2-diisopropyl-5-methylcyclohexane-1-carboxamide is a known cooling agent, WS-3). It carries H319 (causes serious eye irritation) and H411 (toxic to aquatic life with long-lasting effects) hazard statements. Menthol derivatives are widely used as fragrance and cooling ingredients in cosmetics. The acetamide moiety and the isopropyl/methane substitution pattern are consistent with synthetic cooling agents. Under EU Cosmetics Regulation, certain menthol derivatives may be restricted under fragrance allergen provisions if used above threshold concentrations.

Skin benefits

  • Provides cooling sensation
  • Fragrance function
  • Used in oral care and topical formulations for refreshing effect

Known concerns

  • Serious eye irritation (H319)
  • Toxic to aquatic life with long-lasting effects (H411)
  • May be restricted under EU fragrance allergen provisions
  • Cooling agent sensation may mask irritation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.