MENTHYL ETHYCARBAMATE
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A menthol-derived cooling agent and carbamate ester used in skincare for its soothing and sensory-refreshing properties.
Menthyl Ethylcarbamate (CAS 637336-79-9) is the carbamate ester of menthol and ethyl amine. The menthyl moiety provides a cooling sensation via TRPM8 channel activation (the same receptor responsible for menthol's characteristic coolness). The carbamate linkage classifies it as a carbamate ester. Limited specific toxicological data is available for this exact compound; it is structurally distinct from known endocrine disruptors. CosIng lists no restrictions. Sensory irritation (tingling) is possible at high concentrations.
Function
Skin benefits
- Cooling and soothing sensation
- Temporary sensory-refreshing effect
- May help soothe minor skin discomfort
Known concerns
- Possible sensory irritation or tingling at high concentrations
- Limited long-term toxicological data available
- Not well studied for chronic use
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.