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Restricted substance

MESYLOXYBENZYL METHOXYETHYL CHLOROBENZAMIDE

CAS 853081-53-5
12

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A complex chlorinated benzamide bearing a mesylate group. It has no recognised cosmetic function and the alkylating mesylate moiety raises strong genotoxicity concerns, so it is unsuitable for skin contact products.

Skin benefits

  • Listed as a research chemical with no established cosmetic benefit
  • Structural class explored historically for pharmaceutical activity
  • Not associated with any recognised skincare function

Known concerns

  • Mesyloxy leaving groups are classic alkylating motifs linked to mutagenicity
  • No SCCS or CIR opinion supporting use in cosmetic products
  • No defined safe concentration or exposure data
  • Likely captured by EU CMR or unsuitable ingredient framework

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related restricted substances

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.