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METHACRYLAMIDOPROPYLTRIMONIUM CHLORIDE

CAS 51410-72-1
52

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methacrylamidopropyltrimonium Chloride is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Methacrylamidopropyltrimonium Chloride is a quaternary ammonium salt bearing a methacrylamide functional group, used as a conditioning cationic monomer in polymer synthesis. The presence of the methacrylamide moiety and the GHS hazard statements H315 (skin irritation), H319 (eye irritation), and H335 (respiratory irritation) indicate a sensitizing potential. Residual monomer in cosmetic polymers must be controlled. While not listed in EU Annex II or III under Regulation (EC) No 1223/2009, these hazard classifications warrant a lower safety score.

Skin benefits

  • Acts as a conditioning agent in hair care polymer systems

Known concerns

  • Skin irritant (H315) — GHS classified
  • Eye irritant (H319) — GHS classified
  • Respiratory irritant (H335) — GHS classified
  • Methacrylamide moiety may contribute to sensitisation

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.