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Controlled narcotic (banned)

Methadone hydrochloride

CAS 1095-90-5
2

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methadone hydrochloride is a powerful synthetic opioid used by prescription for severe pain and opioid dependence therapy. It is a controlled narcotic and has no place in any cosmetic product.

Skin benefits

  • Prescription opioid analgesic and addiction-treatment medication (not cosmetic)
  • No skin or beauty benefit

Known concerns

  • Schedule II controlled narcotic, illegal in cosmetics worldwide
  • Risk of life-threatening respiratory depression and overdose if absorbed systemically
  • High addiction and abuse potential
  • Prohibited as a cosmetic ingredient under EU Annex II

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related controlled narcotic (banned)s

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.