Conditioning Agent
METHIONYL SH-POLYPEPTIDE-9
Safety score · 0–100
Good
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic fusion peptide with an added methionine start — produced by E. coli fermentation for hair conditioning benefits.
Methionyl sh-Polypeptide-9 is a 166-amino-acid synthetic human-identical peptide with an N-terminal methionine, produced by recombinant E. coli fermentation. CosIng-listed for hair conditioning. The methionine is an artifact of bacterial expression. Contains the standard 20 amino acids in proper sequence. No GHS codes or restrictions. Recombinant peptides undergo purification to remove bacterial components. Large peptide size supports structural protein-like conditioning.
Function
Skin benefits
- Hair conditioning
- Protein-like structural support for hair
Known concerns
- Recombinant E. coli-produced — requires thorough purification
- Large peptide — limited skin penetration (surface conditioning)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related conditioning agents
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.