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METHOXYISOPROPYL ACETATE

CAS 108-65-6
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Also known as 1-methoxy-2-propanol acetate (PGMEA), a glycol ether acetate used as a solvent in cosmetics; no EU cosmetic restrictions and considered safe at low exposure levels.

Methoxyisopropyl acetate (1-methoxy-2-propyl acetate, CAS 108-65-6) is a glycol ether acetate functioning as a solvent in cosmetic formulations, particularly in nail polish and hair spray applications. CosIng shows no regulatory restrictions in EU cosmetic annexes. The compound has a favorable ecotoxicity and human health profile at current workplace and consumer exposure levels, though inhalation exposure in spray products warrants attention to ventilation and use concentrations.

Skin benefits

  • Solvent enabling even distribution of cosmetic actives
  • Used in nail polish formulations

Known concerns

  • Respiratory irritation possible from inhalation in spray applications

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.