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Fragrance ingredient (restricted)

METHOXYPHENYLBUTANONE

CAS 104-20-1
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A raspberry-ketone-related aroma compound flagged by EU scientific reviewers for possible reproductive toxicity. Its use in cosmetics is heavily restricted, and safer fragrance alternatives are widely available.

Skin benefits

  • Used historically as a fragrance and flavor compound for a sweet, raspberry-like scent
  • Has shown some in vitro anti-tyrosinase activity in research settings

Known concerns

  • Classified by SCCS opinion as a potential reproductive toxicant
  • Falls under EU CMR scrutiny restricting use in leave-on cosmetics
  • Limited margin of safety at typical fragrance use levels
  • Skin sensitization potential reported in fragrance allergen literature

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.