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METHYL ACETAMIDE

CAS 79-16-3
48

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methyl Acetamide is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Methyl acetamide is listed in EU Cosmetic Regulation Annex II (II/745), meaning it is prohibited from use in cosmetic products. While it was historically evaluated as a solvent and conditioning agent, studies showed dose-dependent toxicity including liver and kidney effects in animal models, leading to its removal from permissible cosmetic ingredients.

Known concerns

  • Listed in EU Annex II (II/745) — prohibited in cosmetic products
  • Systemic toxicity observed in animal studies at high doses
  • Potential reproductive and developmental effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.