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Solvent

METHYL ACETAMIDE

CAS 79-16-3
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methyl acetamide is a small amide solvent occasionally used to dissolve other ingredients. It is not widely reviewed for cosmetic safety, and related N-alkyl amides carry reproductive concerns at higher doses.

Skin benefits

  • Functions as a solvent in formulation chemistry
  • Can act as a humectant due to amide structure
  • Aids solubilization of certain actives

Known concerns

  • Limited cosmetic safety data published
  • Structural analog of N-methylacetamide which has reproductive toxicity signals
  • Not commonly assessed by SCCS or CIR for topical use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related solvents

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.