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Solvent / intermediate

METHYL ACETOACETATE

CAS 105-45-3
55

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methyl acetoacetate is a small reactive ester used mostly as a solvent or chemical building block, with limited direct use in finished cosmetics. It is irritating in concentrated form but typically present only as a minor processing residue.

Skin benefits

  • Functions as a solvent and chemical intermediate
  • Used in low concentrations as a fragrance component
  • Helps deliver other actives in formulations

Known concerns

  • GHS-classified as causing serious eye irritation
  • May cause mild skin irritation on direct exposure
  • Volatile and flammable in raw form, requiring careful handling

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.