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Skin-soothing active

METHYL ACETYLGLYCYRRHETINOYL HYDROXYPROLINATE

82

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methyl acetylglycyrrhetinoyl hydroxyprolinate is a glycyrrhetinic acid derivative used in skincare to soothe sensitive or reactive skin and support a calmer, less reddened appearance.

Skin benefits

  • Glycyrrhetinic acid derivative with skin-soothing properties
  • Supports calmer-feeling skin and may reduce visible redness
  • Well tolerated at typical use levels

Known concerns

  • Limited large-scale clinical data
  • Rare sensitisation possible in licorice-allergic individuals

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.