Other
Methyl acrylamidoglycolate, if the content of acrylamide >= 0.1%
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
A glyoxylate derivative with severe CMR classifications including suspected carcinogenicity and mutagenicity due to acrylamide content; subject to EU CMR restrictions.
This substance is specifically defined by the EU Cosmetics Regulation (Regulation EC 1223/2009 Annex I) as requiring restriction when acrylamide content is ≥0.1%. Acrylamide is classified as a Category 1B carcinogen and mutagen (H340, H350) under GHS, and the hazard statements (H314 severe skin burns, H317 sensitisation, H340, H350) reflect this. The presence of ≥0.1% acrylamide triggers CMR substance provisions under EU cosmetics law, making this ingredient highly restricted in cosmetic products sold in the EU.
Known concerns
- May cause genetic defects (H340) - Category 1B mutagen
- May cause cancer (H350) - Category 1B carcinogen
- Causes severe skin burns and eye damage (H314)
- May cause an allergic skin reaction (H317)
References
EU CosIng database
European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.