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METHYL O-ANISATE

CAS 606-45-1
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Methyl O-Anisate is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Methyl o-anisate (methyl 2-methoxybenzoate) is used as a fragrance material and shows weak estrogenic activity in in vitro assays, though the relevance to human health at current cosmetic exposure levels is considered low. It is not listed in EU Annex II or III of Regulation 1223/2009. IFRA has issued restrictions due to skin sensitization and phototoxicity concerns, limiting its use in certain product types.

Skin benefits

  • Fragrance material with pleasant aromatic profile

Known concerns

  • Weak in vitro estrogenic activity
  • Skin sensitization and irritation at high concentrations
  • IFRA usage restrictions apply

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.