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Preservative/antimicrobial

METHYLBENZETHONIUM CHLORIDE

CAS 25155-18-4
45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Methylbenzethonium chloride is a quaternary ammonium preservative and antiseptic. Effective but with notable eye and skin irritation potential, so its use is restricted.

Function

ANTIMICROBIAL, ANTISTATIC, DEODORANT, SURFACTANT - CLEANSING

Skin benefits

  • Quaternary ammonium antimicrobial and preservative
  • Effective against bacteria and yeasts
  • Used historically in topical antiseptics

Known concerns

  • Cationic surfactant with eye and skin irritation potential
  • Sensitization risk on broken or sensitive skin
  • Restricted use levels in EU cosmetics (Annex V preservative class)
  • Not recommended in leave-on products without strong justification

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.