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METHYLPYRAZOLYLAMINO CYANOMETHYL ETHYLSULFONYLAZETIDINOPYRAZINE THIENOPYRIMIDINE

45

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient. Exercise caution due to limited available safety data.

This highly engineered molecule combines a thienopyrimidine core (a bicyclic heterocycle related to purine analogues) with a pyrazolylamino group, cyanomethyl, ethylsulfonyl azetidine, and pyrazine moieties. The ethylsulfonyl group is electrophilic and may react with nucleophiles in skin proteins, raising sensitisation potential. No EU regulatory entry exists for this compound.

Skin benefits

  • Complex multi-target potential in skin biology
  • Novel mechanism distinct from conventional cosmetic actives

Known concerns

  • No EU safety assessment
  • Electrophilic groups may cause skin sensitisation
  • Very high molecular weight limits absorption

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.