Emollient
METHYLTHIOHEXYL ISOTHIOCYANATE
Safety score · 0–100
Moderate
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A sulfur-containing isothiocyanate compound — significant sensitizer that can cause allergic skin reactions, respiratory sensitization, and eye damage.
Methylthiohexyl Isothiocyanate (CAS 4430-39-1) is a sulfur-containing organic compound found in cruciferous vegetables (wasabi, horseradish). It carries multiple concerning GHS codes: H317 (skin sensitizer), H318 (serious eye damage), H334 (respiratory sensitizer), H315 (skin irritant), H332 (harmful if inhaled), H335 (respiratory irritant), and H302/H312 (harmful oral/dermal). Signal word: Danger. Despite CosIng listing as emollient/skin conditioner, the hazard profile is concerning.
Function
Skin benefits
- Skin conditioning (claimed)
- Emollient (claimed)
Known concerns
- Skin sensitizer (H317)
- Respiratory sensitizer (H334) — can trigger asthma
- Serious eye damage (H318)
- Skin irritant (H315)
- Harmful if swallowed, inhaled, or via skin (H302/H312/H332)
- Respiratory irritant (H335)
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related emollients
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.