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Metabolic intermediate / skin conditioner

MEVALONOLACTONE

CAS 674-26-0
75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Mevalonolactone is a natural metabolic intermediate involved in cholesterol and lipid synthesis. Promising for barrier support but cosmetic data is limited, so rated cautiously.

Skin benefits

  • Endogenous metabolite in the mevalonate pathway
  • May support skin barrier lipid synthesis at low concentrations
  • Small molecule with good formulation compatibility

Known concerns

  • Limited published cosmetic safety data
  • Functional role in finished skincare not well characterised
  • Stability and conversion to mevalonic acid in formulation needs study

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.