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midodrine

CAS 42794-76-3
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Midodrine is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Midodrine is a pharmaceutical agent classified as an alpha-1 adrenergic agonist registered for medicinal use in the EU (authorised under centralized procedure). It has no legitimate function in cosmetic formulations and would be considered a drug substance if detected in beauty or personal care products. EU market surveillance under Regulation (EC) No 1223/2009 prohibits substances with pharmacological activity not explicitly permitted.

Known concerns

  • Prescription drug substance — not authorized in cosmetics
  • Cardiovascular effects (vasoconstriction, supine hypertension)
  • Would require pharmaceutical authorization if present
  • Not listed in any EU cosmetic positive list

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.