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Restricted synthetic musk

MUSK R1

CAS 3391-83-1
18

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Synthetic musk fragrance of the nitromusk lineage. EU has banned several nitromusks due to neurotoxicity, photoallergy, and bioaccumulation, leaving similar materials unsuitable for cosmetics.

Function

PERFUMING

Skin benefits

  • Synthetic musk fragrance ingredient providing long-lasting scent
  • Historically substituted for natural musk in perfumery

Known concerns

  • Nitromusk-class fragrances (e.g., musk ambrette, moskene) are banned in EU cosmetics
  • Bioaccumulation in human tissue and breast milk reported
  • Photoallergic and neurotoxic effects associated with nitromusks
  • Environmental persistence and aquatic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.