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N-Methylformamide

CAS 123-39-7
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

N-Methylformamide is a cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

N-Methylformamide (HCONHCH3) is a formamide derivative classified as a suspected reproductive toxicant and hepatotoxic agent. It is listed on the EU SVHC (Substances of Very High Concern) candidate list and is subject to REACH authorization requirements. It is not listed in EU CosIng Annexes for cosmetic use and should not be present in cosmetic formulations. Occupational exposure limits exist in several EU member states.

Known concerns

  • EU SVHC candidate list — suspected reproductive toxicant
  • Documented liver toxicity (hepatotoxic) in occupational studies
  • Not authorized for cosmetic use in the EU
  • H351 suspected carcinogen in some assessments

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.