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Toxic solvent

N-Methylformamide

CAS 123-39-7
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A polar amide solvent that is readily absorbed through skin and shows reproductive and hepatic toxicity in animal studies. It is regulated as a reproductive toxin and is not appropriate for cosmetic use.

Skin benefits

  • Useful polar aprotic solvent in chemistry
  • Dissolves a wide range of organics

Known concerns

  • Reproductive and developmental toxicity in animal studies
  • Hepatotoxic at low exposures
  • Readily absorbed through skin
  • Not appropriate as a cosmetic ingredient
  • Listed reproductive toxin in regulatory databases

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.