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Aromatic amine

N,N-dimethyl-p-toluidine

CAS 99-97-8
10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

An aromatic tertiary amine flagged by NTP for clear evidence of carcinogenic activity in animal bioassays. It causes methemoglobinemia and organ toxicity and is not appropriate in cosmetic products.

Skin benefits

  • Used as polymerization accelerator in dental materials
  • Industrial chemistry application

Known concerns

  • IARC classified carcinogenicity concerns
  • Methemoglobinemia risk via aromatic amine metabolism
  • Severe systemic toxicity in animal studies
  • Not suitable for cosmetic skin contact
  • Hepatotoxic and nephrotoxic in NTP studies

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.