N,N,N',N'-Tetraglycidyl-4,4'-diamino-3,3'-diethyldiphenylmethane

Other

30

Caution

CAS Number: 130728-76-6

About N,N,N',N'-Tetraglycidyl-4,4'-diamino-3,3'-diethyldiphenylmethane

A cosmetic ingredient used in product formulations. Its specific function may vary between products. Exercise caution due to limited available safety data.

Detailed Analysis

N,N,N',N'-Tetraglycidyl-4,4'-diamino-3,3'-diethyldiphenylmethane (CAS 130728-76-6) is a tetrafunctional glycidyl ether compound derived from a diphenylmethane backbone with four epoxide groups. The multiple glycidyl (epoxide) groups create significant skin sensitization potential (H317 — may cause allergic skin reaction). The aromatic amine backbone and epoxide functionality together contribute to the mutagenicity concern (H341). The compound also carries H411 (aquatic chronic toxicity), reflecting environmental concern. Residual unreacted monomer in polymers must be controlled. EU cosmetic regulations restrict epoxide monomers in finished products, placing this ingredient in the moderate-to-high concern category.

Skin Benefits

  • ✓ Used as intermediate in manufacturing cosmetic polymers

Known Concerns

  • ⚠ Skin sensitization from glycidyl groups (H317)
  • ⚠ Suspected mutagenicity (H341)
  • ⚠ Chronic aquatic toxicity (H411)
  • ⚠ Residual epoxide monomer requires control per EU Annex III
  • ⚠ Potential for systemic toxicity from epoxide absorption

Safety Score

30

Caution

Based on EU regulatory data, published safety research, and ingredient function analysis.

References

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EU CosIng Database

European Commission cosmetic ingredient registry

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This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.