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Ceramide-mimetic and barrier booster

N-NICOTINOYL PHYTOSPHINGOSINE

83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Phytosphingosine conjugated with nicotinic acid, offering combined ceramide-precursor and niacin-like barrier strengthening, tone-evening and soothing benefits. Highly compatible with sensitive and acne-prone skin.

Skin benefits

  • Combines niacinamide and phytosphingosine activity
  • Strengthens skin barrier and ceramide pool
  • Soothes redness and supports tone
  • Antimicrobial against acne-related microbes

Known concerns

  • Niacin release in small amounts may cause flushing in sensitive users
  • Cost limits in-formula concentration
  • Stability requires care at low pH

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.