Skip to content

Neostigmine iodide

CAS 1212-37-9
25

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Neostigmine Iodide is a cosmetic ingredient. Exercise caution due to limited available safety data.

Neostigmine is a quaternary ammonium compound that reversibly inhibits acetylcholinesterase, used primarily in myasthenia gravis treatment and as a surgical reversal agent. Its pharmacological potency and potential for systemic effects via transdermal absorption make it entirely unsuitable for cosmetic formulations. It is not listed in EU approved cosmetic ingredient databases and would be classified as a prescription medicine.

Known concerns

  • Acetylcholinesterase inhibition (potent pharmacological effect)
  • Prescription-only medicine
  • Prohibited in cosmetic formulations
  • Potential systemic toxicity

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find Neostigmine iodide in your products.

Scan any cosmetic product with LuxSense to see if it contains Neostigmine iodide and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.