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NIACINAMIDE RIBOSIDE MALATE

CAS 2415659-01-5
88

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A NAD+ precursor salt combining nicotinamide riboside with malic acid, supporting cellular energy metabolism and skin barrier function.

Niacinamide riboside is a direct precursor to NAD+, a coenzyme critical for cellular energy production, DNA repair, and sirtuin activity. The malate salt improves bioavailability compared to the parent compound. EU Regulation 1223/2009 does not restrict this ingredient; niacinamide itself is permitted as a skin-conditioning agent. The European Commission's CosIng database lists niacinamide with no restrictions.

Skin benefits

  • Increases NAD+ levels for cellular repair
  • Improves skin barrier function and reduces transepidermal water loss
  • Addresses photodamage and hyperpigmentation

Known concerns

  • May cause mild flushing at very high oral doses
  • Topical use generally well tolerated

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.