Nickel bis(4-cyclohexylbutyrate)
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Nickel Bis(4-cyclohexylbutyrate) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Nickel bis(4-cyclohexylbutyrate) is an organonickel carboxylate. Like other nickel compounds, it is restricted under EU Annex III (entry III/27), requiring Ni equivalent ≤ 0.01% in leave-on products and prohibition in spray products. Nickel is classified as a skin and respiratory sensitiser and CMR 1B under Regulation 1272/2008. Individuals with nickel sensitivity should avoid products containing this compound.
Known concerns
- Skin sensitiser (H317)
- Respiratory sensitiser (H334)
- CMR Category 1B - Suspected reproductive toxicant
- EU Annex III restricted (nickel compounds)
- Prohibited in sprayable cosmetic products
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.