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Nickel bis(4-cyclohexylbutyrate)

CAS 3906-55-6
15

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Nickel Bis(4-cyclohexylbutyrate) is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Nickel bis(4-cyclohexylbutyrate) is an organonickel carboxylate. Like other nickel compounds, it is restricted under EU Annex III (entry III/27), requiring Ni equivalent ≤ 0.01% in leave-on products and prohibition in spray products. Nickel is classified as a skin and respiratory sensitiser and CMR 1B under Regulation 1272/2008. Individuals with nickel sensitivity should avoid products containing this compound.

Known concerns

  • Skin sensitiser (H317)
  • Respiratory sensitiser (H334)
  • CMR Category 1B - Suspected reproductive toxicant
  • EU Annex III restricted (nickel compounds)
  • Prohibited in sprayable cosmetic products

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.