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Nicomethanol Hydrofluoride

CAS 62756-44-9
68

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A fluoride source used in oral care cosmetics at a maximum of 0.15% total fluorine concentration, providing anticaries protection as regulated under EU Annex III.

Nicomethanol hydrofluoride is listed in EU Annex III/1 (substances in oral hygiene products) with a strict maximum fluorine concentration of 0.15% to prevent fluorosis risk. This restriction applies across all fluoride sources in a given product. While effective for caries prevention, the narrow therapeutic window and requirement for precise formulation control place this ingredient in a moderate-risk category for oral cosmetics specifically.

Skin benefits

  • Anti-caries protection in oral hygiene products

Known concerns

  • Fluoride source — restricted to 0.15% total F in EU oral cosmetics
  • Risk of dental fluorosis if overused or swallowed
  • Specific to oral care only — not for skin application

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.