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NICOTINOYL ETHYL SERINATE

66

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nicotinoyl Ethyl Serinate is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Nicotinolyl Ethyl Serinate is a niacinamide-type derivative combining nicotinic acid (niacin) with serine ethyl ester. Niacin and its derivatives are widely used in cosmetics for their barrier-supporting and anti-aging benefits. Under EU CosIng it is listed as a skin-conditioning agent. Some niacin derivatives can cause vasodilation (flushing) and skin irritation, particularly in sensitive individuals. It is not specifically restricted under EU Annex II or III.

Skin benefits

  • Supports skin barrier function
  • May improve skin tone and reduce redness
  • Antioxidant properties from niacin moiety

Known concerns

  • Mild skin flushing or irritation possible, especially with sensitive skin
  • Niacin derivatives can cause vasodilation
  • Avoid contact with broken or eczema-prone skin

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related others

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.