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Humectant

NICOTINOYL SH-NONAPEPTIDE-3

75

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A lab-made peptide used to alter the look of discoloration, pull water into skin, and condition nails. It is usually acceptable in well-formulated products, though sensitive skin can still react.

This is a synthetic or recombinant peptide designed for conditioning or signaling effects, and peptides usually have lower skin penetration than small molecules. At typical cosmetic use levels, the main downside is local irritation, allergy, or formula-dependent sensitivity rather than strong systemic risk.

Function

BLEACHINGHUMECTANTNAIL CONDITIONINGSKIN PROTECTING

Skin benefits

  • Can help brighten the look of skin
  • Hydration support
  • Barrier support

Known concerns

  • Limited independent safety data for novel peptides

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related humectants

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.