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NICOTINOYL SH-PENTAPEPTIDE-4

78

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A niacin-modified peptide designed to improve skin tone, reduce pigmentation, and support overall skin rejuvenation.

Nicotinoyl sh-pentapeptide-4 is a synthetic peptide obtained by reacting niacin (vitamin B3) with a sh-pentapeptide-4 sequence. The niacin moiety provides additional skin-brightening and barrier-supporting benefits alongside the peptide's targeted anti-aging activity. It conforms to INCI standards listed in EU CosIng. The combination of niacin and peptide is generally well-tolerated and suitable for sensitive skin formulations.

Skin benefits

  • Niacin component provides skin brightening and tone evening
  • Peptide supports collagen and reduces signs of aging
  • Combined approach targets both pigmentation and texture

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.