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Skin Conditioning

NICOTINOYL TRIPEPTIDE-35

70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nicotinoyl Tripeptide-35 — a peptide carrying a niacin group. Leverages niacinamide-like claims; evidence is mostly supplier data.

Nicotinoyl Tripeptide-35 is a synthetic tripeptide with a nicotinoyl (niacin, vitamin B3) moiety, designed to combine peptide signalling claims with the well-established niacin/niacinamide profile. Listed in EU CosIng; no SCCS opinion. Use levels are in the parts-per-million range. Public safety and efficacy data are limited. Niacin moieties can cause transient flushing at high topical concentrations, but typical cosmetic exposures are well below that threshold. Evidence level low for this specific peptide.

Function

ANTIOXIDANT

Skin benefits

  • Niacin-peptide hybrid
  • Low-use-level exposure
  • Niacinamide-adjacent claims

Known concerns

  • Thin public safety data
  • No SCCS dossier
  • Proprietary evidence

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.