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Nitrostilbenes, their homologues and their derivatives

10

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A cosmetic ingredient. Exercise caution due to limited available safety data.

Nitrostilbenes are a chemical class of nitroalkene derivatives of stilbene. The EU Cosmetics Regulation Annex III restricts nitrostilbenes and their derivatives at ≥0.1% concentration in cosmetic products. These compounds have raised concerns due to their nitro group reactivity and potential for protein binding, which may lead to skin sensitization and photoallergic reactions. Their restricted status reflects the precautionary approach to nitroaromatic compounds in consumer products.

Known concerns

  • Skin sensitization potential
  • Photoallergic reaction concern
  • Nitro group reactivity
  • Restricted to ≤0.1% in EU cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.