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Banned Substance

Nitroxoline (INN) and its salts

CAS 4008-48-4 Updated
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nitroxoline is an oral antibiotic banned in EU cosmetics (Annex II). Antibiotics are not allowed in topical products to limit antimicrobial resistance.

Skin benefits

  • Used as an oral antibiotic for urinary infections in some countries

Known concerns

  • EU Annex II banned in cosmetics
  • Antibiotic — antimicrobial-resistance concern
  • Photosensitizer (8-hydroxyquinoline class)
  • Not approved for topical cosmetic use

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.