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Banned Substance

(E)-3-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

CAS 82413-20-5
5

Safety score · 0–100

Avoid

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

Afimoxifene (4-hydroxytamoxifen), an active SERM drug — a prescription cancer therapy. Endocrine disruptor and reproductive toxin; not a legal cosmetic ingredient.

Skin benefits

  • No legitimate cosmetic benefit

Known concerns

  • Active SERM drug substance
  • Endocrine disruptor
  • Reproductive toxin
  • Prescription-only/controlled
  • Not cosmetic-permissible

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.