4-Aminosalicylic acid and its salts
Other
Avoid
CAS Number: 65-49-6
About 4-Aminosalicylic acid and its salts
An aromatic amino acid derivative that is completely banned from use in cosmetic products throughout the EU, including as an aerosol propellant.
Detailed Analysis
Under EU Regulation (EC) No 1223/2009 Annex II (entry 353), 4-aminosalicylic acid and its salts are prohibited from being placed on the market or used as substances or in mixtures in concentrations equal to or greater than 0.1% by weight. Entry 353a further prohibits its use as a propellant in aerosols for any use. This is a drug-like compound (anti-tubercular agent historically) with no legitimate cosmetic application. Its structural relationship to para-aminobenzoic acid and potential for sensitisation and systemic effects underpins the prohibition.
Known Concerns
- ⚠ EU Annex II banned substance above 0.1% in cosmetics
- ⚠ EU Annex II banned as aerosol propellant
- ⚠ Potential skin sensitisation
- ⚠ No cosmetic use permitted in the EU
Safety Score
Avoid
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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