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Skin Conditioning

NONAPEPTIDE-16

Updated
70

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

A nine-amino-acid signal peptide used in anti-aging cosmetics at trace levels. Peptides at ppm dosing are typically gentle, though independent safety/efficacy data is sparse.

Function

SKIN CONDITIONING

Skin benefits

  • Marketed as anti-aging signal peptide
  • Used at trace ppm levels in serums
  • Generally well-tolerated peptide chemistry

Known concerns

  • No CIR/SCCS or major regulatory review
  • Efficacy claims rely on supplier data
  • Possible peptide hypersensitivity in rare cases

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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(ARTEMISIA SIEVERSIANA/DIMOCARPUS LONGANA) FLOWER/LEAF/STEM EXTRACT
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(ASPARAGUS COCHINCHINENSIS/LIRIOPE MUSCARI/REHMANNIA CHINENSIS) ROOT EXTRACT
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(CNIDIUM OFFICINALE/COPTIS CHINENSIS/GLYCYRRHIZA URALENSIS) ROOT EXTRACT
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 70
(VETIVERIA ZIZANOIDES ROOT/PUERARIA THUNBERGIANA FLOWER/LEAF/STEM) WATER
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1,3-Dihydroxy-2-propanone
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 70
ABIES ALBA WOOD EXTRACT
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Check your shelf

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.