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Antimicrobial

NONOXYNOL-12 IODINE

CAS - Updated
30

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An iodine-complex of nonoxynol-12 (a nonionic surfactant) — used as a disinfectant preservative. Iodine release, irritation, and the nonoxynol/dioxane combo make it unsuitable for most modern leave-on cosmetics.

Skin benefits

  • Broad-spectrum antimicrobial preservative
  • Iodine-complex disinfectant action

Known concerns

  • Iodine release — sensitisation and thyroid concerns
  • Nonoxynol surfactant carries 1,4-dioxane residue risk
  • Nonoxynol class is restricted in EU detergents
  • Skin and mucous-membrane irritation
  • Not recommended for leave-on cosmetics

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Related antimicrobials

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.