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NONOXYNOL-70

54

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

The most extensively ethoxylated Nonoxynol variant, this surfactant approaches PEG polymer safety levels but is still restricted in EU cosmetics under class-level nonylphenyl regulations.

Nonoxynol-70 is a polyethylene glycol mono(4-nonylphenyl) ether with an average of 70 ethylene oxide units, placing it near the boundary of the nonylphenyl ethoxylate series. Its toxicological profile is substantially more favorable than lower-ethoxylated variants, with minimal nonylphenol generation, low aquatic toxicity, and high water solubility. Nevertheless, EU REACH Annex XVII entry 46a applies to the entire class, and Nonoxynol-70 remains restricted in cosmetic products within the European Union.

Known concerns

  • EU REACH Annex XVII restriction in cosmetic products
  • Trace environmental persistence
  • Nonylphenyl structural class restriction

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.