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NONYL NONOXYNOL-49

CAS 9014-93-1
61

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Nonyl Nonoxynol-49 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

NONYL NONOXYNOL-49 is a nonyl phenyl ether bearing 49 ethoxylate units, making it a large, water-soluble nonionic surfactant. Nonyl phenyl ethoxylates can biodegrade to nonyl phenol, a known endocrine-disrupting substance under EU REACH regulation. The EU's detergents regulation and environmental directives have raised concerns about nonyl phenol precursors. This substance is not specifically listed in EU cosmetics Annexes II or III, but its environmental and endocrine-disruption potential places it in the 'fragrance allergens / Annex III restricted' concern band.

Skin benefits

  • emulsifying
  • cleansing
  • surfactant

Known concerns

  • endocrine disruption potential (nonyl phenol metabolite)
  • environmental toxicity (nonyl phenol)
  • ethylene oxide contamination (potential)
  • 1,4-dioxane contamination (potential)

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.