Skip to content

Norfenefrine hydrochloride

CAS 4779-94-6
28

Safety score · 0–100

Caution

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Norfenefrine Hydrochloride is a cosmetic ingredient. Exercise caution due to limited available safety data.

Norfenefrine is a phenylethanolamine derivative with selective alpha-1 adrenergic agonist activity used as a vasoconstrictor and mydriatic. It carries H302 (harmful if swallowed). As a sympathomimetic drug with cardiovascular effects, it is regulated as a pharmaceutical substance in the EU. Cosmetic use of alpha-adrenergic agonists is limited and subject to specific SCCS assessment.

Known concerns

  • Alpha-adrenergic agonist
  • Oral acute toxicity (H302)
  • Pharmaceutical substance
  • Cardiovascular effects

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

Check your shelf

Find Norfenefrine hydrochloride in your products.

Scan any cosmetic product with LuxSense to see if it contains Norfenefrine hydrochloride and get a full ingredient breakdown with safety scores.

This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.