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Antimicrobial

NORLEUCYL S-FROG OCTAPEPTIDE-1 D-LEUCYL D-LYSYL TRIPEPTIDE-90 AMIDE

65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

A 13-aa synthetic peptide blending frog-derived antimicrobial sequences, D-leucine, D-lysine, and norleucine. Designed for anti-acne and anti-sebum effects; data is mostly proprietary, so use with awareness.

Function

ANTIMICROBIALANTI-SEBUM

Skin benefits

  • Antimicrobial activity from frog-derived octapeptide motif
  • D-amino-acid stabilization improves resistance to skin proteases
  • Targets sebum-related bacteria in oily/acne-prone skin

Known concerns

  • Antimicrobial peptides may disturb skin microbiome with chronic use
  • Limited public safety data beyond INCI/manufacturer claims
  • Synthetic D-amino acids are not naturally cleared by all enzymes

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related antimicrobials

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.