normethadone
Safety score · 0–100
Avoid
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
A synthetic opioid related to methadone that is not permitted in cosmetic products and is regulated as a medicinal substance.
Normethadone (1-methadone, nor-methadone; 6-dimethylamino-4,4-diphenylhexan-3-one) is a synthetic opioid analgesic and the primary metabolite of methadone. It is a controlled substance and is not authorized for cosmetic use. In the EU, it falls under the scope of drug legislation rather than cosmetics. Annex II of the EU Cosmetics Regulation lists substances not permitted, and while not explicitly enumerated, opioid-analgesic compounds are understood to be excluded from cosmetic use.
Known concerns
- Prohibited for cosmetic use in the EU
- Synthetic opioid — regulated as a drug/medicinal product
- No cosmetic safety data available
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.