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Antimicrobial

O-TOLYL BIGUANIDE

CAS 93-69-6
42

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

O-Tolyl biguanide — an aromatic-amine biguanide mainly known as a rubber-vulcanisation accelerator. Rare in modern cosmetics; class profile includes contact-allergen risk for PPD-sensitive users.

Skin benefits

  • Mild antimicrobial activity in hair-care
  • Industrially used as a rubber-vulcanisation accelerator

Known concerns

  • Aromatic-amine class with documented skin sensitisation
  • Mainly industrial use; rare in modern cosmetics
  • Limited modern cosmetic safety review
  • Potential as cross-reactant for PPD-allergic users

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

Related antimicrobials

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.