O-TOLYL BIGUANIDE
Other
Moderate
CAS Number: 93-69-6
About O-TOLYL BIGUANIDE
O-Tolyl Biguanide is a cosmetic ingredient used in product formulation. In pure/concentrated form, may cause skin irritation. Exercise caution due to limited available safety data.
Detailed Analysis
O-Tolyl Biguanide (CAS 93-69-6) is a substituted biguanide compound structurally related to chlorhexidine. It functions as an antimicrobial agent and preservative. Biguanides work by disrupting bacterial cell membranes. While effective against a broad range of microorganisms, biguanides are known to cause contact sensitisation in some individuals. The compound has limited modern safety assessment data specifically for cosmetic use. Given the known sensitisation profile of the biguanide class and limited specific data, a cautious safety rating is warranted.
Skin Benefits
- ✓ Broad-spectrum antimicrobial activity
- ✓ Preservative function — extends product shelf life
Known Concerns
- ⚠ Biguanide class — known potential for contact sensitisation
- ⚠ Limited modern cosmetic safety assessment data
- ⚠ Structurally related to chlorhexidine — shares some toxicological concerns
- ⚠ May cause allergic contact dermatitis
Safety Score
Moderate
Based on EU regulatory data, published safety research, and ingredient function analysis.
References
EU CosIng Database
European Commission cosmetic ingredient registry
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Download LuxSenseThis information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional for skin concerns or allergies.