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OCTA (SH-POLYPEPTIDE-178)

83

Safety score · 0–100

Good

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An eight-repeat synthetic polypeptide designed for advanced skin-care applications including anti-aging and skin-barrier support formulations.

Octa (sh-Polypeptide-178) is a synthetic peptide composed of eight repeats of sh-Polypeptide-178. High-repeat synthetic peptides like this are engineered for cosmetic use with large molecular sizes that limit systemic absorption. Not restricted under EU Cosmetics Regulation 1223/2009 and considered safe for topical applications.

Skin benefits

  • Potential anti-aging and firming benefits
  • May support skin smoothness and barrier health

Known concerns

  • Individual hypersensitivity reactions possible but rare

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.