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Oral care active (amine fluoride)

OCTADECENYL-AMMONIUM FLUORIDE

CAS - Updated
65

Safety score · 0–100

Fine

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

An amine fluoride used in toothpaste and mouthwash to deliver fluoride for caries prevention. EU lists it as a permitted oral cosmetic ingredient within strict fluoride concentration limits to avoid fluorosis in children.

Function

ANTIPLAQUE, ORAL CARE

Skin benefits

  • Provides fluoride ions for caries prevention in oral care
  • Substantive to tooth enamel due to surfactant tail
  • Listed for cosmetic use in COSMILE Europe

Known concerns

  • Fluoride compounds carry strict use-level limits in toothpaste
  • Risk of dental fluorosis with chronic overuse in children
  • Quaternary ammonium portion may irritate mucosa at high concentrations
  • Ingestion hazard for young children

References

EU

EU CosIng database

European Commission cosmetic ingredient registry: regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve, so always read the physical product label and consult a healthcare professional for personal concerns.