Other
OCTOXYNOL-16
Safety score · 0–100
Fine
Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.
About
Octoxynol-16 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.
Octoxynol-16 with 16 ethylene oxide units is in the higher-EO range where surfactant irritation diminishes significantly. The longer EO chain reduces the compound's ability to penetrate or disrupt skin lipid barriers. The primary regulatory risk is not direct consumer safety but environmental: octylphenol ethoxylates are classified under REACH as requiring priority attention for aquatic environmental risk. Many EU member states have recommended substitution away from alkylphenol ethoxylates in cosmetic products.
Known concerns
- Environmental concern: precursor to endocrine-disrupting octylphenol
- Low irritation potential but not absent at high concentrations
- REACH/European regulatory pressure encouraging alternatives
References
EU CosIng database
European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.
Related others
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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.