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OCTOXYNOL-5

CAS 9002-93-1
54

Safety score · 0–100

Moderate

Derived from EU CosIng regulatory status, PubChem hazard data and published research. How we score.

About

Octoxynol-5 is a cosmetic ingredient used in product formulations. Exercise caution due to limited available safety data.

Octoxynol-5 (5 mol EO average) sits at the lower end of the mid-range for the octoxynol series, giving it higher surface activity and correspondingly higher irritation potential. The octylphenyl moiety is the structural liability: in the EU, octylphenol and its ethoxylates face regulatory pressure due to PBT (persistent, bioaccumulative, toxic) classification of their degradation products. Cosmetic use in rinse-off products is the more responsible application; leave-on use warrants caution and low concentration.

Known concerns

  • Skin and eye irritation at moderate to high concentrations
  • Environmental endocrine-disruption concern from octylphenol
  • Not recommended for leave-on cosmetic products by some safety assessors

References

EU

EU CosIng database

European Commission cosmetic ingredient registry — regulatory status, restrictions, authorised functions.

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This profile is for educational purposes and does not constitute medical advice. Regulatory status and scientific understanding evolve — always read the physical product label and consult a healthcare professional for personal concerns.